Floating Drug Delivery Systems Using Metronidazole as a Model Drug Part I: By Effervescent Method
Gastric retentive dosage forms are highly useful for the wickelfalzrohre delivery of many kinds of drugs.The use of floating dosage forms (FDFs) is one of the methods used to achieve prolonged gastric residence time (GRT).Formulation of Metronidazole (MDZ) as FDF provides an opportunity for both local and systemic drug action for eradication of Hel